Selank + Semax (10/10mg)

Selank + Semax is a dual-peptide research blend combining a synthetic analog of the immunomodulatory peptide tuftsin (Selank) with a synthetic analog of the ACTH(4-10) fragment (Semax).

Researchers use this combination to study neuropeptide signaling, neurotrophic-factor expression, and GABAergic and monoaminergic pathway modulation under controlled laboratory conditions.

This compound is provided by GENIQ exclusively for scientific research and not for human or animal use.

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What Is Selank + Semax?

Selank + Semax is a synthetic peptide blend developed for research on neuropeptide signaling in the central nervous system.

Selank is a heptapeptide derived from tuftsin, a naturally occurring fragment of immunoglobulin G, extended with a Pro-Gly-Pro sequence for stability. Semax is a heptapeptide analog of the ACTH(4-10) fragment, also stabilized with a C-terminal Pro-Gly-Pro motif.

Researchers use this blend to investigate neurotrophic-factor expression, GABA-receptor modulation, and neuropeptide-mediated gene-expression changes in cellular and preclinical models.

GENIQ provides this compound solely for controlled laboratory research, not for human or animal use.

Peptide Overview

This blend merges two peptides commonly used in neuroscience research:

Selank:
A tuftsin-analog heptapeptide studied for its influence on GABAergic neurotransmission, enkephalin-degrading enzyme activity, and cytokine-expression models.

Semax:
An ACTH(4-10) analog investigated for its effects on BDNF and TrkB expression, monoaminergic signaling, and neuronal-survival models in vitro.

Laboratory studies evaluate how this peptide combination may influence:
• BDNF and neurotrophin-receptor expression
• GABA-receptor subunit expression and GABAergic signaling
• Enkephalin-degrading enzyme activity
• Neuropeptide-mediated gene-expression patterns in preclinical models
These findings are strictly from research environments.

All findings remain limited to preclinical and in-vitro experimental environments.

History of Selank + Semax

Semax was developed in Russia during the 1980s at the Institute of Molecular Genetics as a stabilized analog of the ACTH(4-10) fragment, retaining the fragment’s neuropeptide activity while removing hormonal effects associated with the full ACTH sequence.

Selank followed from the same research program in the 1990s, applying the Pro-Gly-Pro stabilization approach to tuftsin, an immunomodulatory tetrapeptide.

Researchers began pairing these peptides to investigate how two structurally related, stabilized neuropeptides act on overlapping neurotrophic and neurotransmitter pathways. The combination remains of interest for in-vitro and preclinical examination of neuropeptide signaling.

Peptide Structure

Selank Sequence:
Thr-Lys-Pro-Arg-Pro-Gly-Pro
Molecular Formula: C33H57N11O9

Semax Sequence:
Met-Glu-His-Phe-Pro-Gly-Pro
Molecular Formula: C37H51N9O10S

Selank Semax product struct

Certificates of Analysis

Selank + Semax (10mg / 10mg)

Research Findings

Research models analyzing the dual activity of Selank and Semax commonly explore:

• Neurotrophic signaling: Measuring changes in BDNF and TrkB expression following peptide exposure in cellular models.
• GABAergic modulation: Examining Selank-related changes in GABA-receptor subunit expression.
• Gene-expression profiling: Investigating transcriptomic responses in hippocampal and immune-cell models.
• Neuropeptide stability: Comparing degradation kinetics of Pro-Gly-Pro stabilized peptides in vitro.
These data represent controlled in-vitro and preclinical studies, not clinical outcomes.

These findings reflect laboratory experiments only and do not indicate clinical outcomes.

References

1. Dolotov O.V., et al. “Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus.” Brain Research, 2006.

2. Volkova A., et al. “Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission.” Frontiers in Pharmacology, 2016.

3. Kolomin T., et al. “Transcriptomic response of rat hippocampus and spleen cells to single and chronic administration of the peptide Selank.” Doklady Biochemistry and Biophysics, 2010.

FAQ

What type of research is this peptide blend used for?

It is used to study neuropeptide signaling, neurotrophic-factor expression, and GABAergic and monoaminergic pathway modulation.

Yes. Every GENIQ peptide includes a COA verifying identity and purity.

No. It is not FDA-approved and not intended for human or veterinary administration.

No. GENIQ does not give any guidance related to reconstitution, dosing, or application.

Only trained laboratory researchers in controlled scientific environments.

Research Use Only

All GENIQ compounds are intended strictly for laboratory research.
 Not for human or animal consumption, medical use, or therapeutic application.

Nothing in this document should be interpreted as medical advice or as approval for use outside controlled scientific environments.

Selank + Semax is a dual-peptide research blend combining a synthetic analog of the immunomodulatory peptide tuftsin (Selank) with a synthetic analog of the ACTH(4-10) fragment (Semax).

Researchers use this combination to study neuropeptide signaling, neurotrophic-factor expression, and GABAergic and monoaminergic pathway modulation under controlled laboratory conditions.

This compound is provided by GENIQ exclusively for scientific research and not for human or animal use.

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