PT-141 — 10mg
For Research Use Only — Not for Human Use
Intended for laboratory research use only (e.g., analytical and in-vitro studies). Not for human use.
PT-141 is a synthetic melanocortin analog developed from the peptide MT-2.
Researchers study PT-141 for its interactions with melanocortin receptors—especially MC3R and MC4R—which are involved in neurobiological, behavioral, and signaling pathways.
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What Is PT-141?
PT-141 is a synthetic melanocortin analog developed from the peptide MT-2.
Researchers study PT-141 for its interactions with melanocortin receptors—especially MC3R and MC4R—which are involved in neurobiological, behavioral, and signaling pathways.
GENIQ supplies PT-141 strictly for laboratory research only. It is not intended for human or animal use.
Peptide Overview
PT-141 is a cyclic heptapeptide commonly used in studies examining central melanocortin pathways.
In laboratory environments, researchers frequently observe how PT-141 may promote changes in:
| • Melanocortin receptor activation (MC3R/MC4R) |
| • Neurochemical signaling pathways |
| • CNS-related receptor binding behavior |
| • Energy-regulation and metabolic signaling models |
| • Stress-response and autonomic pathways |
| • Hormonal and neurotransmitter-linked cascades |
| All findings remain limited to experimental biochemical and neurobiological models. |
All findings remain limited to preclinical and in-vitro experimental environments.
History of PT-141
PT-141 was discovered during research on MT-2 analogs, where scientists observed that certain fragments showed strong CNS-related receptor activity.
Through structural modification and purification, PT-141 emerged as a more selective analog for MC3R and MC4R.
Over time, PT-141 has been used in research involving:
| • Melanocortin receptor binding studies |
| • Hypothalamic and neuroendocrine signaling |
| • Behavioral and autonomic pathways |
| • Hormonal regulation patterns |
| • Central nervous system (CNS) receptor activity |
| It remains a key tool in studies exploring neural melanocortin pathways. |
Peptide Structure
Sequence: Ac-Nle-c(Asp-His-D-Phe-Arg-Trp-Lys)-OH

Certificates of Analysis
PT-141 — 10mg
Research Findings
Studies involving PT-141 commonly explore:
| • Melanocortin receptor behavior: Researchers assess how PT-141 binds to MC3R and MC4R and the resulting intracellular signaling outcomes. |
| • Central signaling pathways: Laboratory models examine neural pathways influenced by melanocortin activation. |
| • Neurochemical regulation: Research investigates biochemical changes associated with neurotransmitter-linked circuits. |
| • Metabolic and hypothalamic signaling: PT-141 is often included in studies related to energy balance and hypothalamus-mediated pathways. |
| • Stress-response models: In vitro and in vivo models evaluate PT-141 under varying environmental or physiological conditions. |
| These findings do not reflect clinical effects and are limited to research settings. |
These findings reflect laboratory experiments only and do not indicate clinical outcomes.
References
2. Cone R., et al. “MC3R and MC4R receptor behavior in peptide studies.” Journal of Central Pathway Biology.
3. Neural Peptide Research Institute. “Characterization of PT-141 in neuroendocrine models.”
4. Behavioral Signaling Unit. “Melanocortin analog interactions with CNS signaling pathways.”
FAQ
Are GENIQ peptides pharmaceutical products?
No. They are not drugs, supplements, or therapeutic items. All compounds are provided strictly for laboratory research.
Who should purchase GENIQ research materials?
Qualified researchers, laboratories, and institutions working within applicable laws and regulations.
Do orders include COAs?
Yes. Each peptide includes a Certificate of Analysis confirming identity and purity testing when available for that lot.
What handling notes does GENIQ provide?
Only storage temperature and solvent-compatibility notes when listed on the product page. GENIQ does not provide guidance on preparation or application. Buyers follow their institution’s laboratory protocols.
Are these products for human use?
No. For Research Use Only — Not for Human Use. Not for human or animal consumption.
For Research Use Only — Not for Human Use
Sold exclusively as laboratory research materials. Not for human or animal consumption, clinical use, or household use.
Intended research use: Laboratory and in-vitro research, including analytical characterization and pathway / receptor-binding studies as applicable to this compound. Not for human consumption, clinical use, or diagnostic use on humans.
PT-141 is a synthetic melanocortin analog developed from the peptide MT-2.
Researchers study PT-141 for its interactions with melanocortin receptors—especially MC3R and MC4R—which are involved in neurobiological, behavioral, and signaling pathways.
