Tesamorelin / Ipamorelin (15mg / 5mg)
Tesamorelin / Ipamorelin is a dual-peptide research blend combining a stabilized growth hormone-releasing hormone analog (Tesamorelin) with a selective growth hormone secretagogue receptor peptide (Ipamorelin).
Researchers use this combination to study the interaction between GHRH-receptor signaling and ghrelin-receptor pathways under controlled laboratory conditions.
This compound is provided by GENIQ exclusively for scientific research and not for human or animal use.
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What Is Tesamorelin / Ipamorelin?
Tesamorelin / Ipamorelin is a synthetic peptide blend developed for research on pituitary signaling and growth hormone axis regulation.
Tesamorelin is a 44-amino-acid GHRH analog stabilized with an N-terminal trans-3-hexenoyl group, which increases its resistance to enzymatic degradation in experimental systems. Ipamorelin is a pentapeptide that selectively engages the growth hormone secretagogue receptor (GHSR).
Researchers use this blend to investigate dual-pathway stimulation of somatotroph cells, hormone-pulse modeling, and downstream signaling cascades.
GENIQ provides this compound solely for controlled laboratory research, not for human or animal use.
Peptide Overview
This blend merges two peptides commonly used in endocrine signaling research:
Tesamorelin:
A stabilized GHRH(1-44) analog studied for its impact on pituitary receptor activation, sustained GHRH-receptor signaling, and lipid-metabolism models.
Ipamorelin:
A selective GHSR (growth hormone secretagogue receptor) agonist investigated for its role in ghrelin-related cellular communication, receptor specificity, and downstream signaling mechanisms.
| Laboratory studies evaluate how this peptide combination may influence: |
| • Somatotroph cell signaling |
| • cAMP pathway activation |
| • GHRH-receptor and ghrelin-receptor co-stimulation |
| • Visceral adipose and lipid-metabolism models in preclinical settings |
| These findings are strictly from research environments. |
All findings remain limited to preclinical and in-vitro experimental environments.
History of Tesamorelin / Ipamorelin
Tesamorelin was developed as a stabilized analog of the full-length 44-amino-acid GHRH sequence, designed to resist rapid enzymatic cleavage while preserving native receptor interaction. It became one of the most extensively characterized GHRH analogs in the scientific literature.
Ipamorelin was introduced in the late 1990s as the first highly selective growth hormone secretagogue, showing minimal interaction with other pituitary hormones, which made it a valuable tool for isolating ghrelin-receptor pathways.
Researchers began pairing these peptides to investigate how simultaneous GHRH-receptor and GHSR activation behaves in experimental hormone-regulation studies. The combination remains of interest for in-vitro examination of pituitary dynamics and endocrine-signaling interactions.
Peptide Structure
Tesamorelin Sequence:
(trans-3-Hexenoyl)-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH₂
Ipamorelin Sequence:
Aib-His-D-2-Nal-D-Phe-Lys-NH₂
Certificates of Analysis
Tesamorelin / Ipamorelin (15mg / 5mg)
Research Findings
Research models analyzing the dual activity of Tesamorelin and Ipamorelin commonly explore:
| • GHRH-receptor and GHSR pathway interactions: Studying combined receptor signaling when both pathways are activated. |
| • Pituitary-cell responsiveness: Examining how somatotrophs respond to dual-peptide stimulation. |
| • Intracellular messenger activity: Including cAMP activation, downstream gene-expression changes, and receptor-signal amplification. |
| • Lipid-metabolism modeling: Using Tesamorelin to observe GHRH-analog effects on adipose-tissue signaling in preclinical models. |
| These data represent controlled in-vitro and preclinical studies, not clinical outcomes. |
These findings reflect laboratory experiments only and do not indicate clinical outcomes.
References
2. Stanley T.L., et al. “Effect of Tesamorelin on Visceral Fat and Liver Fat in HIV-Infected Patients With Abdominal Fat Accumulation.” JAMA, 2014.
3. Raun K., et al. “Ipamorelin, the first selective growth hormone secretagogue.” European Journal of Endocrinology, 1998.
4. Ferdinandi E.S., et al. “Non-clinical pharmacology and safety evaluation of TH9507, a human growth hormone-releasing factor analogue.” Basic and Clinical Pharmacology and Toxicology, 2007.
FAQ
What type of research is this peptide blend used for?
It is used to study GHRH-receptor and ghrelin-receptor pathway interactions, pituitary signaling, and hormone-pulse modeling.
Does GENIQ provide a Certificate of Analysis?
Yes. Every GENIQ peptide includes a COA verifying identity and purity.
Is this product approved for human or animal use?
No. It is not FDA-approved and not intended for human or veterinary administration.
Can GENIQ provide instructions regarding preparation or use?
No. GENIQ does not give any guidance related to reconstitution, dosing, or application.
Who should handle this compound?
Only trained laboratory researchers in controlled scientific environments.
Research Use Only
All GENIQ compounds are intended strictly for laboratory research.
Not for human or animal consumption, medical use, or therapeutic application.
Nothing in this document should be interpreted as medical advice or as approval for use outside controlled scientific environments.
Tesamorelin / Ipamorelin is a dual-peptide research blend combining a stabilized growth hormone-releasing hormone analog (Tesamorelin) with a selective growth hormone secretagogue receptor peptide (Ipamorelin).
Researchers use this combination to study the interaction between GHRH-receptor signaling and ghrelin-receptor pathways under controlled laboratory conditions.
This compound is provided by GENIQ exclusively for scientific research and not for human or animal use.
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